|Pack Size||28 TAb|
Ledifos, Hepcvir L, Hepcinat LP, Resof L, Lisof, Ledviclear, Myhep Lvir
Ledipasvir and Sofosbuvir Tablets
Hetero, Cipla, Natco, Dr. Reddy's, Mylan
We sell Hepcinat from Natco at best prices and we also have Sofosbuvir at very good discounted prices in Caddiline Exports Pvt.Ltd at Nagpur or other Indian Regions as well as outside India to any other Countries of the world.
Hepcinat - (Sofosbuvir) is a prescription drug manufactured by Natco & licenced by for Hepatitis C, with a high cure rate. It is a once-a-day prescription medicine that is used with other antiviral medicines to treat chronic (lasting a long time) hepatitis C (Hep C) infection in adults. It is advised that the medicine should not be taken alone & still unknown if it is safe for children.
We are Looking Queries from Foreign Countries & Exports Only.
SoviHep 400mg (Sofosbuvir) is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. Sofosbuvir is a prodrug and after ingestion it is rapidly converted to GS-331007, the predominant circulating drug that accounts for greater than 90% of the systemically active drug. This triphosphate compound mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in chain termination. The active form GS-461203 targets the NS5B catalytic site and acts as a non-obligate chain terminator. The active compound (GS-461203) does not inhibit host DNA polymerases, RNA polymerases, or mitochondrial RNA polymerase.SoviHep 400mg is available as a 400 mg tablet. The recommended dose of sofosbuvir is 400 mg taken orally once daily, with or without food. The 400 mg dose of sofosbuvir should be used, regardless of the patient's genotype and prior hepatitis C treatment experience. No dose adjustment is needed for mild-to-moderate renal impairment or with mild, moderate, or severe hepatic impairment. SoviHep 400mg has been very well-tolerated in clinical trial. The most common adverse effects observed with sofosbuvir, when used in combination with ribavirin, have been fatigue and headache. Sofosbuvir is pregnancy category B.The major concern with drug interactions exists with medications that are strong inducers of intestinal P-gp, such as rifampin and St. John's wort, since these compounds may significantly lower sofosbuvir and GS-331007 levels. The coadministration of sofosbuvir with the following medications is not recommended because these medications may significantly lower sofosbuvir levels: